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October 2000 Cover
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A University of California professor presented data at an annual meeting of the American Orthopedic Association suggesting that protease inhibitor use may be connected to avascular necrosis of the femoral head. Of the
18 HIV patients involved in the study, all of whom had avascular necrosis, 11 were taking protease inhibitors. While 10 of the 11 protease inhibitor users did not have another risk factor for the condition, six of the seven
not using protease inhibitors had other risk factors.
Editor's Note: from Pharmaceutical Journal
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