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October 2004 Cover
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The diabetes drug Avandia (rosiglitazone) might help reduce body fat redistribution and diabetes-like metabolic changes that can occur when patients are on certain AIDS cocktails, announced US researchers. Highly active antiretroviral therapy (HAART), which helps keep
HIV-infected patients alive and healthy, can have severe side effects for those taking the drugs. Some patients may simply lose body fat, while others can see odd buildups of fat around their shoulders or, worse, around internal organs. Many patients lose fat in their faces-- giving them a
gaunt appearance-- while gaining it elsewhere in the body.
A team from Massachusetts General Hospital and Harvard Medical School found that daily doses of Avandia helped HIV patients better handle naturally occurring insulin.
Editor's Note: from Reuters
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