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June 2000 Cover
June 2000 Cover

 HIV Digest HIV Digest Archive  
June 2000 Email this to a friend
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Thymic Reconstitution Possible After Combination Therapy

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New research indicates that reconstituting thymocytes which appear after antiretroviral therapy in HIV-positive mice are functional and have normal T-cell receptor distribution. The findings suggest that proper antiretroviral therapy and improvement in thymic function could help HIV patients gain immunity response. In the study, mice were infected with HIV and then treated with zidovudine, dideoxyinosine, and indinavir, and watched for the presence of thymocytes.

Editor's Note: from the Journal of Virology


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