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AIDS researcher David Ho said recently that failure rates for the new AIDS cocktails will most likely go up over time and that better drugs are needed. Ho, head of the Aaron Diamond AIDS Research Center in New
York, noted that the drug resistance problem will increase.
Henry Chang, research director of the AIDS Healthcare Foundation in Los Angeles, added that new drugs aimed at inhibiting integrase might be less susceptible to drug resistance. According to Chang, the
gene that produces integrase appears to mutate at a much lower rate that those that make other enzymes, such as protease.
Editor's Note: from Reuters
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